Phosphorous Tribromide
CAS # 7789-60-8
Phosphorus Tribromide is a highly reactive phosphorus halide used as a brominating and activation agent in pharmaceutical, agrochemical, and specialty chemical synthesis.
Description:
Phosphorus Tribromide is a phosphorus halide used as a brominating and activation agent in pharmaceutical, agrochemical, and specialty chemical manufacturing. Known for its ability to efficiently convert alcohols and acids into brominated intermediates, it enables precise synthesis and high-value product development. Manufacturers rely on Phosphorus Tribromide for its strong reactivity, predictable performance, and suitability for both laboratory and industrial-scale operations.
General Properties:
Molecular Formula: PBr₃
Appearance: Colorless to pale yellow liquid
Boiling Point: ~173 °C
Solubility: Reacts with water
Applications:
Pharmaceutical & Fine Chemical Synthesis
Used to convert alcohols into alkyl bromides and prepare key intermediates for active pharmaceutical ingredients.
Agrochemical Manufacturing
Supports synthesis of herbicide, insecticide, and specialty crop-protection intermediates.
Specialty Chemical Intermediates
Used in production of brominated compounds, catalysts, and advanced functional materials.
Research & Laboratory Applications
Preferred reagent for controlled bromination and functional group transformations.
Chemical Manufacturing
Applied in processes requiring efficient bromide introduction and activation chemistry.
Advantages:
High Reactivity & Conversion Efficiency: Enables fast and effective bromination reactions with strong yields.
Versatile Chemical Intermediate: Supports a wide range of organic transformations across industries.
Suitable for Scale-Up: Used successfully in both pilot and commercial manufacturing.
Supports Advanced Synthesis: Ideal for producing high-value brominated intermediates.
Safety & Handling:
Phosphorus Tribromide is a corrosive and moisture-reactive chemical and must be handled with appropriate precautions.
Reacts with water to form hydrobromic and phosphorous acids
Causes severe skin and eye burns
Vapors may irritate respiratory tract
Harmful if inhaled
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